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Laboratorio di Immunofarmacologia

Attività di Ricerca Barbara Bottazzi Pubblicazioni
PUBBLICAZIONI SELEZIONATE

Reading PC, Bozza S, Gilbertson B, Tate M, Moretti S, Job ER, Crouch EC, Brooks AG, Brown LE, Bottazzi B, Romani L, Mantovani A. (2008).

“Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses.”

J Immunol 180(5): 3391-8.

 

Inforzato A, Rivieccio V, Morreale AP, Bastone A, Salustri A, Scarchilli L, Verdoliva A, Vincenti S, Gallo G, Chiapparino C, Pacello L, Nucera E, Serlupi-Crescenzi O, Day AJ, Bottazzi B, Mantovani A, De Santis R, Salvatori G. (2008).

“Structural characterization of PTX3 disulphide bond network and its multimeric status in cumulus matrix organization.”

J. Biol. Chem.: M708535200.

 

Scarchilli L, Camaioni A, Bottazzi B, Negri V, Doni A, Deban L, Bastone A, Salvatori G, Mantovani A, Siracusa G, Salustri (2007).

“PTX3 interacts with inter-alpha-trypsin inhibitor: implications for hyaluronan organization and cumulus oophorus expansion.”

J Biol Chem 282(41): 30161-70.

 

Bottazzi, B., C. Garlanda, G. Salvatori, P. Jeannin, A. Manfredi, and A. Mantovani. (2006).

“Pentraxins as a key component of innate immunity.”

Curr Opin Immunol 18:10-15.    

 

Camozzi, M., S. Zacchigna, M. Rusnati, D. Coltrini, G. Ramirez-Correa, B. Bottazzi, A. Mantovani, M. Giacca, and M. Presta. (2005).

“Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivo.”

Arterioscler Thromb Vasc Biol 25:1837-1842.

 

Jeannin P, Bottazzi B, Sironi M, Doni A, Rusnati M, Presta M, Maina V, Magistrelli G, Haeuw J F, Hoeffel G, Thieblemont N, Corvaia N, Garlanda C, Delneste Y, Mantovani A

“Complexity and complementarity of outer membrane protein a recognition by cellular and humoral innate immunity receptors.”

Immunity 2005; 22: 551-560

 

Garlanda C, Bottazzi B, Bastone A, Mantovani A

“Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.”

Annu Rev Immunol  2005; 23: 337-366

 

Salustri A, Garlanda C, Hirsch E, De Acetis M, Maccagno A, Bottazzi B, Doni A, Bastone A, Mantovani G, Beck-Peccoz P, Salvatori G, Mahoney D J, Day A J, Siracusa G, Romani L, Mantovani A.

“PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.”

Development  2004; 131: 1577-1586

 

Camozzi M, Moroni E, Bottazzi B, Peri G, Indraccolo S, Amadori A, Mantovani A, Presta M.

“Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis.”

Blood  2004; 104: 92-99

 

Nauta A J, Bottazzi B, Mantovani A, Salvatori G, Kishore U, Schwaeble W J, Gingras A R, Tzima S, Vivanco F, Egido J, Tijsma O, Hack E C, Daha M R, Roos A.

“Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.”

Eur J Immunol  2003; 33: 465-473

 

Rolph M S, Zimmer S, Bottazzi B, Garlanda C, Mantovani A, Hansson G K.

“Production of the long pentraxin PTX3 in advanced atherosclerotic plaques.”

Arterioscler Thromb Vasc Biol  2002; 22: e10-e14

 

Garlanda C, Hirsch E, Bozza S, Salustri A, De Acetis M, Nota R, Maccagno A, Riva F, Bottazzi B, Peri G, Doni A, Vago L, Botto M, De Santis R, Carminati P, Siracusa G, Altruda F, Vecchi A, Romani L, Mantovani A.

“Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response.”

Nature  2002; 420: 182-186

 

Mueller B, Peri G, Doni A, Torri V, Landmann R, Bottazzi B, Mantovani A.

“Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients.”

Crit Care Med  2001; 29: 1404-1407

 

Rovere P, Peri G, Fazzini F, Bottazzi B, Doni A, Bondanza A, Zimmermann V S, Garlanda C, Fascio U, Sabbadini M G, Rugarli R, Mantovani A, Manfredi A.

“The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells.”

Blood  2000; 96: 4300-4306

 

Bottazzi B, Vouret-Craviari V, Bastone A, De Gioia L, Matteucci C, Peri G, Spreafico Fabio, Pausa M, D'Ettorre C, Gianazza E, Tagliabue A, Salmona M, Tedesco F, Introna M, Mantovani A.

“Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.”

J Biol Chem  1997; 272: 32817-32823

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